You betcha, folks. Pokemon Omega Ruby and Alpha Sapphire have been confirmed from the Pokémon company, and the entire world is in chaos.
There really isn't a whole lot to say here. Mega Evolutions for Latios and Latias are credible now. FireRed and LeafGreen remakes are possible now. And every main region will be available on the 3DS somehow; remember HG/SS has both Johto and Kanto.
Oh, who am I kidding. SPECULATION TIME!! But not now.
Here we come, November 2014!